5-bromodeoxyuridine-induced differentiation of a neuroblastoma.
نویسندگان
چکیده
5-Bromodeoxyuridine induces the differentiation of mouse neuroblastoma C1300 to cells that morphologically resemble mature neurons. The induced differentiation can take place in the absence of DNA synthesis. This suggests that the halogenated pyrimidine need not be incorporated into DNA to alter the phenotype of the cell.
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عنوان ژورنال:
- Proceedings of the National Academy of Sciences of the United States of America
دوره 67 1 شماره
صفحات -
تاریخ انتشار 1970